Why is Telomerase Activation a Target for Cancer Therapy?
Because telomerase activity is relatively low in normal somatic cells but high in cancer cells, it represents a potential target for cancer therapy. Inhibiting telomerase could limit the replicative potential of cancer cells, leading to their eventual senescence or death. Various strategies are being explored, including small molecule inhibitors, antisense oligonucleotides, and immunotherapeutic approaches targeting telomerase components.
