What are the Current Strategies to Overcome Efflux Pump-Mediated Drug Resistance?
Several strategies are being explored to overcome efflux pump-mediated drug resistance in cancer. These include:
Developing efflux pump inhibitors that are more selective and less toxic. Using nanoparticle-based drug delivery systems to bypass efflux pumps. Combining efflux pump inhibitors with traditional chemotherapy drugs. Exploring gene editing techniques to downregulate efflux pump expression.
