What are the Current Therapeutic Approaches Targeting Ras Dimerization?
Several strategies are being explored to target Ras dimerization in cancer therapy:
Small Molecules: Compounds that can disrupt Ras dimerization or inhibit its interaction with downstream effectors. Peptide Inhibitors: Designed to specifically bind to dimerization interfaces, preventing Ras dimer formation. Monoclonal Antibodies: Targeting extracellular domains of receptor tyrosine kinases (RTKs) that interact with Ras.
