Why is Understanding Ras Dimerization Important for Cancer Therapy?
Targeting Ras-driven cancers has been a major challenge due to the "undruggable" nature of Ras proteins. However, understanding the mechanisms of Ras dimerization opens new avenues for therapeutic interventions. By disrupting Ras dimerization, it may be possible to inhibit the aberrant signaling pathways activated by oncogenic Ras, thereby providing a potential strategy for treating Ras-driven cancers.