Future research aims to better understand the immunological mechanisms underlying the GVT effect and to develop novel therapies that can harness this phenomenon more effectively. Areas of focus include: 1. Biomarker Identification: Finding biomarkers that predict the strength of the GVT effect and the risk of GVHD. 2. Advanced Cellular Therapies: Developing more sophisticated [CAR-T cells]( ) and other adoptive cell therapies. 3. Combination Therapies: Testing combinations of immunotherapies and traditional treatments to maximize the anti-tumor response.