Despite its advantages, IVIM has some limitations:
1. Complexity of Analysis: The need for multiple b-values and complex fitting algorithms can make data acquisition and analysis challenging. 2. Sensitivity to Motion: Patient motion can affect the accuracy of IVIM measurements, requiring robust motion-correction techniques. 3. Standardization: Lack of standardization in IVIM acquisition protocols and parameter calculation can lead to variability in results across different studies and institutions.
