IVIM MRI employs multiple b-values to capture diffusion and perfusion information. Low b-values are sensitive to both diffusion and perfusion, whereas high b-values are primarily sensitive to diffusion. By fitting the signal decay curve, parameters such as the diffusion coefficient (D), pseudo-diffusion coefficient (D*), and perfusion fraction (f) can be extracted. These parameters provide insights into tissue cellularity and microvascular environment, which are critical in cancer assessment.
