Several cardioprotective strategies have been researched and implemented, including:
Beta-blockers: These medications help reduce heart rate and blood pressure, providing a protective effect against chemotherapy-induced cardiotoxicity. Studies have shown that beta-blockers like carvedilol can help prevent heart damage.
ACE inhibitors and ARBs: Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers are used to manage hypertension and heart failure, conditions that can be exacerbated by cancer treatments.
Dexrazoxane: This is a chelating agent that has been shown to reduce the risk of heart damage in patients receiving anthracyclines by binding to iron and preventing the formation of free radicals.
Lifestyle Modifications: Encouraging patients to engage in regular physical activity, maintain a healthy diet, and manage stress can have a profound effect on heart health during cancer treatment.