What are the Major Findings from Genomic Research in Cancer?
Genomic research has led to several groundbreaking discoveries, including:
The identification of driver mutations in oncogenes and tumor suppressor genes, which are critical for cancer development. The recognition of genomic instability and mutational signatures that characterize different cancer types. The discovery of epigenetic changes such as DNA methylation and histone modification that play a role in cancer. The understanding of tumor heterogeneity, which explains why different cells within the same tumor can have distinct genetic profiles.
