mammalian target of rapamycin

What is the Mammalian Target of Rapamycin (mTOR)?

The Mammalian Target of Rapamycin (mTOR) is a crucial serine/threonine kinase that regulates cell growth, proliferation, motility, survival, protein synthesis, and transcription. mTOR forms two distinct complexes known as mTORC1 and mTORC2, which have different components and functions. mTORC1 is sensitive to rapamycin, a potent immunosuppressant and anti-cancer agent, whereas mTORC2 is less sensitive.

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