What Are the Mechanisms Behind Genistein's Anticancer Effects?
Several mechanisms have been proposed to explain genistein's anticancer properties:
Apoptosis Induction: Genistein can induce apoptosis (programmed cell death) in cancer cells by activating pathways like the mitochondrial and death receptor pathways. Cell Cycle Arrest: It can halt the cell cycle at specific checkpoints, particularly the G2/M phase, thereby inhibiting cancer cell division. Anti-Angiogenesis: Genistein inhibits the formation of new blood vessels (angiogenesis) that supply nutrients to tumors. Antioxidant Activity: Its antioxidant properties help in neutralizing free radicals, reducing oxidative damage to DNA.
