What Are the Potential Benefits of Targeting G6PD in Cancer?
Targeting G6PD offers several potential benefits in cancer therapy:
Selective Toxicity: Cancer cells often have higher G6PD activity than normal cells, making them more susceptible to G6PD inhibitors. Overcoming Drug Resistance: By targeting metabolic pathways, G6PD inhibitors might overcome resistance mechanisms that affect conventional therapies. Combination Therapy: G6PD inhibitors can be used alongside other treatments, such as chemotherapy and radiotherapy, to enhance their efficacy.
