What are the Potential Carcinogenic Effects of Styrene Metabolism?
The formation of styrene oxide is a critical step in understanding the carcinogenic potential of styrene. This metabolite can form DNA adducts, which are alterations in DNA that may lead to mutations and ultimately cancer. Studies have shown that styrene oxide can induce genotoxic effects, such as sister chromatid exchanges and chromosomal aberrations. These genetic alterations are key precursors to cancer development.
