What are the Potential Side Effects of BET Inhibitors?
While BET inhibitors hold promise as anticancer agents, they can also cause side effects. Common side effects observed in clinical trials include thrombocytopenia, gastrointestinal disturbances, fatigue, and anemia. Additionally, due to the broad role of BET proteins in gene regulation, there is a risk of off-target effects that could impact normal cellular functions. Continuous research is required to optimize the therapeutic window and minimize adverse effects.
