What Are the Potential Therapeutic Strategies Targeting BUBR1?
Given its pivotal role in maintaining chromosomal stability, therapeutic strategies targeting BUBR1 are being developed. These include small molecule inhibitors that disrupt its function and gene therapy approaches to restore its expression in cancers with reduced BUBR1 levels. Additionally, combination therapies that target BUBR1 along with other cell cycle regulators are being explored to enhance cancer treatment efficacy.
