While FOLFOX can be highly effective, it is also associated with a range of side effects. Common side effects include nausea, vomiting, diarrhea, and fatigue. Patients may also experience neuropathy, which is a tingling or numbness in the hands and feet caused by oxaliplatin. This condition can sometimes be severe and may necessitate dose adjustments or discontinuation of the drug. Other potential side effects include mouth sores, low blood cell counts, and an increased risk of infection.
