The process of in vivo screening typically involves several key steps:
Selection of an appropriate model: The choice of model depends on the type of cancer being studied and the specific research objectives. Tumor implantation: Cancer cells or tissues are implanted into the chosen model organism. Treatment administration: The potential anticancer agent is administered to the organism, often at varying doses and schedules. Monitoring and data collection: Researchers monitor the organism for changes in tumor size, metastasis, and overall health. Data is collected on the drug's efficacy and toxicity. Analysis and interpretation: The collected data is analyzed to determine the drug's potential as a viable cancer treatment.