What are the Therapeutic Implications of EMT in Cancer?
Understanding EMT has significant therapeutic implications in cancer treatment. EMT contributes to therapeutic resistance, making it a critical target for intervention. Inhibitors targeting EMT-related pathways or transcription factors are being explored to prevent or reverse EMT, thereby reducing metastasis and improving the efficacy of conventional therapies. For example, inhibiting TGF-β signaling has shown promise in preclinical studies.
