What are the therapeutic implications of miR-34a in cancer treatment?
Given its tumor-suppressive properties, miR-34a represents a promising target for cancer therapy. Strategies to restore or enhance miR-34a function in cancer cells are being explored. These include the use of miR-34a mimics, which are synthetic molecules that can mimic the activity of endogenous miR-34a, and gene therapy approaches to deliver miR-34a to cancer cells. Clinical trials are underway to evaluate the safety and efficacy of miR-34a-based therapies.
