What Cancers are Commonly Associated with SMARCA4 Mutations?
SMARCA4 mutations are particularly prevalent in non-small cell lung cancer (NSCLC) and small cell carcinoma of the ovary (SCCOHT). In NSCLC, SMARCA4 mutations are often associated with a poorer prognosis. In SCCOHT, SMARCA4 mutations are almost universally present, making it a key diagnostic marker for this rare and aggressive cancer.
