Gynecomastia can occur due to a variety of factors in cancer patients. These include:
Hormonal Imbalances: Cancers such as testicular or adrenal tumors can disrupt normal hormone levels, increasing estrogen or decreasing testosterone, which can lead to gynecomastia. Medications: Certain drugs used in cancer treatment, like anti-androgens, chemotherapy agents, and some targeted therapies, can cause gynecomastia as a side effect. Liver Disease: Liver dysfunction, often seen in advanced cancer, can impair the metabolism of hormones, contributing to gynecomastia.