choline kinase

Can Choline Kinase be a Therapeutic Target?

Given its role in cancer metabolism, ChoK represents a promising therapeutic target. Several strategies are being explored:
1. Small Molecule Inhibitors: Compounds that specifically inhibit ChoK activity have shown anti-cancer effects in preclinical models.
2. RNA Interference (RNAi): Silencing ChoK gene expression using siRNA or shRNA can reduce tumor growth.
3. Combination Therapies: Targeting ChoK in conjunction with other therapies, such as chemotherapy or radiotherapy, may enhance treatment efficacy.

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