Which Cancers Show Increased Choline Kinase Activity?
Several types of cancer exhibit elevated ChoK activity, including: - Breast Cancer: Higher ChoKα expression is associated with aggressive subtypes and poor prognosis. - Lung Cancer: Elevated levels of phosphocholine have been detected in lung tumors. - Prostate Cancer: Increased ChoK activity correlates with tumor grade and progression. - Colorectal Cancer: Overexpression of ChoK is linked to advanced disease stages.