The exact cause of medulloblastomas is not well understood. However, several genetic mutations and chromosomal abnormalities have been linked to the development of these tumors. Research has identified that alterations in pathways such as the SHH (Sonic Hedgehog), WNT (Wingless), and MYC oncogene are involved in tumor formation. Genetic syndromes such as Gorlin syndrome and Turcot syndrome also increase the risk of developing medulloblastomas.
