immunosuppressive microenvironment

What Cells Contribute to the Immunosuppressive Microenvironment?

Several types of cells contribute to the immunosuppressive microenvironment:
T regulatory cells (Tregs): These cells suppress T cell activity and promote tumor tolerance.
Myeloid-derived suppressor cells (MDSCs): These cells inhibit the function of T cells and natural killer (NK) cells.
Tumor-associated macrophages (TAMs): These macrophages often promote tumor growth and suppress immune responses.
Cancer-associated fibroblasts (CAFs): These fibroblasts can produce molecules that suppress immune cell infiltration and function.

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