anal pap tests

What Do the Results Mean?

The results of an anal Pap test can be:
Normal: No abnormal cells detected.
ASC-US: Atypical squamous cells of undetermined significance. This finding means that some cells look unusual but not necessarily cancerous.
LSIL: Low-grade squamous intraepithelial lesion. Indicates mild abnormalities, often associated with HPV infection.
HSIL: High-grade squamous intraepithelial lesion. Indicates more serious abnormalities that could lead to cancer.
ASC-H: Atypical squamous cells, cannot exclude HSIL. Abnormal cells are present, and HSIL cannot be ruled out.
Abnormal results may require follow-up testing, such as high-resolution anoscopy (HRA) or a biopsy, to determine the severity of the abnormality and the appropriate course of action.

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