What is Humoral Hypercalcemia of Malignancy (HHM)?
Humoral Hypercalcemia of Malignancy (HHM) is a paraneoplastic syndrome commonly associated with cancer. It is characterized by elevated calcium levels in the blood, primarily due to the overproduction of parathyroid hormone-related protein (PTHrP) by malignant cells. This condition is most frequently seen in patients with squamous cell carcinomas, renal cell carcinoma, breast cancer, and certain lymphomas.
