Lactate dehydrogenase A (LDHA) is an enzyme that plays a crucial role in the conversion of pyruvate to lactate during glycolysis. This reaction is particularly significant in the context of hypoxic conditions, where oxygen levels are low, and cells rely on anaerobic metabolism to generate energy. LDHA is one of the five isoforms of lactate dehydrogenase and is widely expressed in various tissues, including muscle and liver.