What is Latency Associated Nuclear Antigen (LANA)?
Latency Associated Nuclear Antigen (LANA) is a protein encoded by the Kaposi’s sarcoma-associated herpesvirus (KSHV), also known as Human Herpesvirus 8 (HHV-8). LANA plays a crucial role in the virus's ability to establish latency within host cells, which is a state where the virus persists in the host without producing new virions. This protein is essential for the maintenance of the viral episome, ensuring the virus remains in the host cell's nucleus.
