How do cell membranes and signaling pathways contribute to cancer?
The cell membrane is involved in various signaling pathways that regulate cell growth, survival, and apoptosis. Cancer cells often exhibit altered membrane composition and receptor expression, which can enhance proliferative signaling and resistance to cell death. Aberrant activation of pathways like PI3K/AKT and MAPK is common in cancer, leading to increased proliferation and survival. Understanding these changes is crucial for developing targeted therapies.