What is the significance of extracellular matrix (ECM) in cancer?
The extracellular matrix provides structural support and regulates cellular behavior. In cancer, ECM composition is often altered, facilitating tumor growth and metastasis. Cancer cells can modify the ECM by secreting enzymes like matrix metalloproteinases (MMPs), which degrade ECM components and allow cancer cells to invade surrounding tissues. Targeting ECM remodeling is a promising approach to inhibit cancer progression.
In summary, cellular structures play pivotal roles in the development and progression of cancer. Understanding these changes is crucial for the development of effective cancer treatments and diagnostics. As research advances, targeting specific cellular structures and pathways holds the promise of improving cancer therapy outcomes.
