What changes occur in the cytoskeleton of cancer cells?
The cytoskeleton is crucial for maintaining cell shape, enabling movement, and facilitating cell division. In cancer cells, the cytoskeleton undergoes significant reorganization, which can enhance invasive and metastatic capabilities. For instance, changes in actin filament dynamics and the overexpression of proteins such as gelsolin or fascin can promote cancer cell motility. Targeting cytoskeletal components and their regulatory pathways may help prevent metastasis.
