LKB1, also known as STK11, is a serine/threonine kinase that plays a crucial role in cellular energy homeostasis and metabolism. It is encoded by the STK11 gene, located on chromosome 19p13.3. LKB1 is a master kinase that phosphorylates and activates a group of downstream kinases, including AMP-activated protein kinase (AMPK), which are involved in maintaining cellular energy balance.
