Platelet-Derived Growth Factor Receptors (PDGFR) are cell surface tyrosine kinase receptors that play a critical role in regulating cell growth, survival, and differentiation. PDGFRs are activated by binding to platelet-derived growth factors (PDGFs), leading to a cascade of signaling events within the cell. There are two main types of PDGFRs: PDGFR-α and PDGFR-β.