What are Common Applications of ChIP in Cancer Studies?
ChIP is used in various applications within cancer research, including:
- Identifying Oncogene Binding Sites: Researchers can use ChIP to identify where oncogenes, such as c-Myc or p53, bind to the genome. - Studying Histone Modifications: By examining histone modifications, such as acetylation or methylation, researchers can understand the epigenetic changes that promote or suppress cancer. - Investigating Drug Targets: ChIP can help in identifying potential targets for new cancer therapies by elucidating how certain drugs affect the binding of proteins to DNA.