What is the Connection Between Calcium and Cancer Metastasis?
Calcium plays a significant role in cancer metastasis. Elevated calcium levels can stimulate the expression of adhesion molecules and proteases, facilitating the detachment and invasion of cancer cells into surrounding tissues. Furthermore, calcium signaling is involved in the epithelial-mesenchymal transition (EMT), a process by which cancer cells acquire migratory and invasive characteristics, contributing to metastatic spread.
