What Role Does Calcium Play in Cancer Cell Proliferation?
Calcium is a critical second messenger in cellular signaling pathways that promote cell proliferation and survival. Altered calcium signaling can contribute to the uncontrolled growth characteristic of cancer. Cancer cells often exhibit dysregulated calcium channels and pumps, leading to increased intracellular calcium levels. This alteration can support cancer cell proliferation, migration, and invasion, and may also confer resistance to apoptotic signals.
