What is the Epidermal Growth Factor Receptor (EGFR)?
The Epidermal Growth Factor Receptor (EGFR) is a transmembrane protein that belongs to the family of receptor tyrosine kinases. It is involved in the regulation of cell growth, survival, proliferation, and differentiation. Upon binding with its specific ligands, such as the epidermal growth factor (EGF), the receptor undergoes dimerization and autophosphorylation, initiating a cascade of downstream signaling pathways.
