alternative hypotheses

What is the Metabolic Hypothesis of Cancer?

The metabolic hypothesis posits that cancer is fundamentally a disease of altered metabolism. This theory traces back to Otto Warburg's observation that cancer cells predominantly produce energy through glycolysis, even in the presence of ample oxygen, a phenomenon known as the Warburg effect. Researchers are now exploring how targeting metabolic pathways can provide new avenues for cancer treatment, such as disrupting the energy supply specifically to cancer cells.

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