What is the Prognostic Value of EGFR Amplification?
The prognostic significance of EGFR amplification varies depending on the cancer type and context. In some cancers, such as glioblastoma, EGFR amplification is associated with a more aggressive tumor phenotype and worse clinical outcomes. In other cancers, the presence of EGFR amplification may predict responsiveness to EGFR-targeted therapies, making it a valuable biomarker for treatment selection.
