What is the Relationship Between Phospholipids and Cancer Metabolism?
Cancer cells exhibit altered metabolism to support their rapid growth and survival, often referred to as the Warburg effect. These metabolic changes include increased synthesis and turnover of phospholipids to meet the demands of rapidly proliferating cells. Enzymes involved in phospholipid metabolism, such as choline kinase and fatty acid synthase, are often upregulated in cancer, making them potential targets for therapeutic intervention.