How Do Phospholipids Influence Cancer Immunotherapy?
The tumor microenvironment, which includes immune cells, is influenced by the lipid composition of cancer cell membranes. Certain phospholipids can modulate immune cell function, affecting the efficacy of immunotherapy. For example, phosphatidylserine exposure on the surface of cancer cells can lead to the suppression of immune responses, providing a potential target for enhancing immunotherapeutic strategies.
