What is the Role of EVs in Tumor Microenvironment?
The tumor microenvironment (TME) consists of various cell types, including immune cells, fibroblasts, and endothelial cells. EVs facilitate communication within the TME, influencing cancer progression and therapy resistance. For instance, EVs from tumor-associated fibroblasts can enhance cancer cell invasiveness, while those from immune cells can either promote or inhibit tumor growth depending on their content.
