What is the Role of Heparin Derivatives in Cancer Treatment?
The primary role of heparin derivatives in cancer treatment revolves around their ability to inhibit angiogenesis and metastasis. These derivatives can block the activity of growth factors like VEGF (Vascular Endothelial Growth Factor), which are essential for new blood vessel formation. Additionally, they can interfere with enzymes like heparanase that degrade the extracellular matrix, thus preventing cancer cells from invading and spreading.