What is the Role of Reed-Sternberg Cells in Hodgkin Lymphoma?
Reed-Sternberg cells play a central role in the pathology of Hodgkin lymphoma. They release various cytokines and chemokines that attract other immune cells to the tumor microenvironment, leading to the characteristic inflammatory response observed in Hodgkin lymphoma. This inflammatory milieu contributes to the growth and survival of Reed-Sternberg cells and the progression of the disease.
