What is the significance of Acetyl-CoA Carboxylase (ACC) in cancer?
Acetyl-CoA Carboxylase (ACC) is an enzyme that converts acetyl-CoA to malonyl-CoA, a critical step in fatty acid synthesis. ACC is often upregulated in cancer cells to meet the increased demand for fatty acids. Inhibition of ACC can reduce lipid synthesis, impair tumor growth, and enhance the efficacy of other cancer treatments.
