What role does Lipoprotein Lipase (LPL) play in cancer metabolism?
Lipoprotein Lipase (LPL) is an enzyme that hydrolyzes triglycerides in lipoproteins into free fatty acids, which can be taken up by cancer cells for energy production and membrane synthesis. Many cancers exhibit elevated LPL activity, which facilitates lipid uptake and promotes tumor growth. Inhibiting LPL can reduce the availability of fatty acids, potentially starving cancer cells and inhibiting their growth.
