What is the Significance of Tumor Microenvironment Modulation?
The tumor microenvironment (TME) plays a crucial role in cancer progression and resistance to therapy. Novel constructs aim to modulate the TME to make it less conducive for cancer growth and more supportive of immune cell activity. This can involve targeting stromal cells, altering the extracellular matrix, or neutralizing immunosuppressive factors within the TME. By modifying the TME, these approaches can enhance the effectiveness of existing therapies.
