What Methods are Used in Preclinical Testing for Cancer?
Several methods are utilized in the preclinical testing of cancer treatments: 1. In Vitro Studies: These involve testing new drugs on cancer cell lines grown in the lab. Researchers can assess the drug's ability to kill cancer cells or inhibit their growth. 2. In Vivo Studies: These involve testing new treatments in animal models, such as mice or rats, that have been implanted with human tumors. This helps evaluate the drug's efficacy and safety in a living organism. 3. Ex Vivo Studies: These involve testing new treatments on cancer tissues obtained from patients, providing a more accurate representation of how the drug might perform in humans. 4. Computational Models: These use computer simulations to predict a drug's behavior and potential effects based on its chemical structure and known biological interactions.