Addressing hierarchical barriers requires a multi-faceted approach. Biologically, advancements in [genomic sequencing](https://) and molecular profiling can enhance the understanding of tumor heterogeneity and lead to more effective targeted therapies. Clinically, improving early detection through the development of reliable biomarkers and screening programs is essential.
Systemically, strengthening healthcare infrastructure and ensuring equitable access to advanced treatments can mitigate disparities. Enhancing the efficiency and reach of clinical trials can also accelerate the development of new therapies. Socio-economically, increasing [public awareness](https://) and education about cancer, along with policies to improve healthcare access and affordability, can significantly improve outcomes.